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A. Explain why an inherited deficiency in complement components C 3 or C 4 can result in less efficient clearance of immune complexes from the blood and lymph than normal. B. What clinical symptoms can this lead to? C. What is the only known effect of deficiencies in complement components C5-C9? Explain this effect. | Numerade
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Complement C3 - targeted intervention as a novel host modulation therapy in periodontal diseases Gingivitis and periodontitis are prevalent inflammatory diseases of the periodontal tissues. Current treatments are often ineffective or do not prevent disease recurrence. Uncontrolled complement activation and resulting chronic gingival inflammation is a hallmark of periodontal diseases. We have developed a novel safe and efficacious treatment by using the complement 3-targeted therapeutic, AMY-101,
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