Heavy Metals Series (Video 3 of 4) Chelation therapy can be administered safely and effectively with an experienced practitioner though it is not without potential risks and harms. Chelation is the specific term used for detoxification of heavy metals. Chelation requires drugs in order to remove heavy metals quickly. There are supplements that can assist in chelation, but they pale in comparison to the power of chelating drugs. The chelating drugs are: EDTA (IV only) DMPS (IV or oral drugs) DMSA