Dec 4, 2023 · The present study was designed to investigate the role of endogenous sulfur dioxide (SO2) in vascular smooth muscle cell (VSMC) proliferation, and explore the possible …

The goal of this review is to integrate previous studies into a discussion of MAPKs and MAPK-mitochondria signaling in cardiac diseases, such as myocardial infarction (ischemia), …

Mar 16, 2025 · In this review, we explore the research conducted in recent years (primarily over the past five years) on the relationship between the MAPK signaling pathway and …

May 22, 2014 · The present study firstly demonstrated that SO2 exerted a negative regulation of VSMC proliferation via suppressing the Erk/MAPK pathway mediated by cAMP/PKA signaling.

Sep 18, 2012 · Here, we provide a dynamic model of feedback and crosstalk for the three major MAPKs (ERK, p38, JNK) and protein kinase B (AKT) signaling. The model incorporates …

Dec 29, 2015 · These findings suggested that endogenous SO 2 was a novel gasotransmitter in the cardiovascular system and provided a new therapy target for cardiovascular diseases.

Nov 1, 2014 · The goal of this review is to integrate previous studies into a discussion of MAPKs and MAPK–mitochondria signaling in cardiac diseases, such as myocardial infarction …

Aug 31, 2024 · This review explores the mechanisms of cross-talk between key signaling pathways, such as the MAPK, PI3K/Akt, and NF-κB pathways, and their implications for …

The tremendous progress made in the identification and characterization of the components of the MAPK cascades has led to an explosion in translational research attempting to link these …

Dec 19, 2023 · Here, we review the existing knowledge of how individual members of the large and diverse group of MAP3Ks sense specific stress signals through largely non-redundant …