In silico antibody accessibility analysis indicates that ectodomain epitopes are transiently exposed, while MPER epitopes are virtually always occluded in the pre-fusion trimer.

Abstract: Brain tumor segmentation plays a critical role in accurate diagnosis and treatment planning but remains challenging due to complex tumor boundaries and variations across MRI sequences.

Abstract: In this paper, the production decision optimisation problem is investigated, and a multi-objective optimisation model is solved using Genetic Algorithm (GA). Firstly, for the problem of ...

This important study introduces a new biology-informed strategy for deep learning models aiming to predict mutational effects in antibody sequences. It provides solid evidence that separating ...

(BPT) - Like every year, many of us make New Year's resolutions and try to stick to them, but broad, all-or-nothing changes often set us up for failure and can make mental health struggles even worse.