Researchers developed a way to directly reprogram human glial cells into PV interneurons without passing through a stem‑cell stage.

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Studies on diseases that affect the human brain are usually based on animal models which cannot reproduce the complexity of human neuropathies. Therefore, these methodologies often fail when applied ...

Researchers from Monash University in Melbourne and The University of Western Australia have demonstrated how a reprogramming method imitates embryonic epigenetic reset. Transient naive treatment (TNT ...

Scientists have produced stem cells from the endangered Grévy's zebra using human reprogramming factors. Further comprehensive gene analyses identified key genes that are also found in human and mouse ...

Zhou’s study, "TBX20 improves contractility and mitochondrial function during direct human cardiac reprogramming," was recently published in Circulation. The most common cause of death worldwide is ...

Mammalian hearts have almost no ability to grow new heart muscle cells, called cardiomyocytes, after birth. Thus, dead tissue after an adult heart attack is not repaired with new cardiomyocytes. It is ...

Scientists from Kyoto University’s Institute for Integrated Cell-Material Sciences (iCeMS) and Wildlife Research Centre have produced stem cells from the endangered Grévy’s zebra using human ...