Calcific aortic valve disease sits at the confluence of multiple world-wide epidemics of aging, obesity, diabetes, and renal dysfunction, and its prevalence is expected to nearly triple over the next ...

Cardiovascular disease is the leading global cause of morbidity and mortality. New technologies are needed to improve mechanistic understanding and inform therapeutic strategies. Human-centric cardiac ...

ruscs provides tools for simulating how rumors spread. The package implements the Maki-Thompson model with support for quasi-stationary method and control strategies for the simulation.

The performance of a vehicle’s suspension system is critical for ensuring ride comfort, maintaining road holding, and guaranteeing stability. Traditional suspension designs are predominantly based on ...

The Gillespie algorithm provides statistically exact methods for simulating stochastic dynamics modeled as interacting sequences of discrete events including systems of biochemical reactions or ...

Archipelagoes present exciting opportunities to understand the process of adaptive radiation. To better understand the roles of hybridization, geographic isolation, and trait divergence in adaptive ...

This important study introduces a fully differentiable variant of the Gillespie algorithm as an approximate stochastic simulation scheme for complex chemical reaction networks, allowing kinetic ...

The quality of radiotherapy auto-segmentation training data, primarily derived from clinician observers, is of utmost importance. However, the factors influencing the quality of clinician-derived ...

aMolecular and Integrative Biosciences Research Programme, Faculty of Biological and Environmental Sciences, University of Helsinki, Helsinki, Finland bOrganismal and Evolutionary Biology Research ...