This study presents a large, systematically curated catalog of non-canonical open reading frames (ncORFs) in human and mouse by reanalyzing nearly 400 Ribo-seq datasets using a standardized pipeline; ...

The genetic code is the recipe for life, and provides the instructions for how to make proteins, generally using just 20 amino acids. But certain groups of microbes have an expanded genetic code, in ...

There are few hard and fast rules in the study of life, but perhaps the closest we get is the central dogma of molecular biology: DNA is transcribed to RNA, which gets translated into proteins. The ...

DNA sequencing is one of today's most critical scientific fields, powering leaps in humanity's understanding of genetic causes of cancer, neurodegenerative diseases, and diabetes. One issue facing the ...

Forbes contributors publish independent expert analyses and insights. Amir is Founder of AI unicorn Avathon & Boeing/SC JV, SkyGrid. Recently, a friend asked me a question that's been floating around ...

An illustration of E. coli. Scientists have been racing to shrink the genetic code of this bacterium. Kateryna Kon / Science Photo Library via Getty Images The DNA of nearly all life on Earth is made ...

The DNA of nearly all life on Earth contains many redundancies, and scientists have long wondered whether these redundancies served a purpose or if they were just leftovers from evolutionary processes ...

In a giant feat of genetic engineering, scientists have created bacteria that make proteins in a radically different way than all natural species do. By Carl Zimmer At the heart of all life is a code.

Barbara Rae-Venter, a 76-year-old patent attorney living in Marina, California, thought she'd spend her retirement leisurely playing tennis, traveling, and indulging in her favorite pastime: ...

To overcome the inherent challenge of translation termination interference caused by stop codon reprogramming in mammalian cells, researchers from Peking University led by Chen Peng from College of ...

The Indigenous peoples of the Bolivian highlands are survivors. For thousands of years they have lived at altitudes of more than two miles, where oxygen is about 35 percent lower than at sea level.

The technique used on a 9½-month-old boy with a rare condition has the potential to help people with thousands of other uncommon genetic diseases. KJ Muldoon was born with a rare genetic disorder, ...