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Mapping pre-myelinating oligodendrocytes: New mouse line links neuronal activity to cell survival
Nerve fibers in the brain and spinal cord are wrapped in an insulating sheath known as myelin. For a long time, this barrier, ...
Cell line development (CLD) follows a process that has only changed slightly since it was established in the early days of biopharmaceutical development. The steps to create a stable, manufacturing ...
Bill Skarnes and team established and characterized a stable iPSC line, KOLF2.1J, to act as a high-quality baseline platform for modeling human disease. About 15 years ago, researchers discovered a ...
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Researchers provide a global catalog of human pluripotent stem cell lines for clinical use
To date, more than 100 clinical trials with human pluripotent stem cell (hPSC)-derived products have been initiated worldwide and an increasing number of potential hPSC-derived clinical products have ...
U.S. government researchers have made a significant step forward in developing a fully automated process for cell-line development. The National Institute of Allergy and Infectious Diseases (NIAID), ...
Researchers discovered that a long-misunderstood protein plays a key role in helping chromosomes latch onto the right “tracks ...
Even its ancestry is an enigma. Phylogenetic trees place Sukunaarchaeum as a “deep-branching” member of the domain ...
ShineOn’s proprietary product, SOB100, a HLA-G targeted exosome drug delivery carrier, has passed the U.S. FDA IND review and ongoing Phase I study, making it as a first-in-class–potential HLA-G ...
During a live event, Matthew Lunning, DO, discussed key factors that determine whether patients should receive CAR T-cell ...
“These findings by our University of Hawai‘i Cancer Center research team show that drug resistance is not necessarily the end ...
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