Haplotype inference is an indispensable technique in medical science, especially in genome-wide association studies. Although the conventional method of inference using the expectation-maximization ...

Many disease resistance traits in plants have a polygenic background and the disease phenotypes are modified by environmental factors. As a consequence, the phenotypic values usually show a ...

This example estimates the normal SSM of the mink-muskrat data using the EM algorithm. The mink-muskrat series are detrended. Refer to Harvey (1989) for details of this data set. Since this EM ...

We show that the ECM algorithm can always be constructed to converge at the same or approximately the same rate as the EM algorithm. The construction is based on the well-known conjugate directions ...

Berkeley Lab researchers have developed the first 3-D atomic-scale model of P22 virus that identifies the protein interactions crucial for its stability. This is a great example of how to exploit ...

A simple explicit formula is provided for the matrix of second derivatives of the observed data log-likelihood in terms of derivatives of the criterion function (the conditional expectation of the ...