A decade ago, the Nobel Prize in Chemistry was awarded to a trio of researchers for the development of super-resolved fluorescence microscopy. The announcement at the time stated that the researchers’ ...

To unravel the complexities of biological phenomena, scientists have long relied on microscopy to visualize the intricate details of their specimens, including tissue architecture, cell morphology, ...

Even those who maintain that super-resolution microscopy is a powerful tool of biological discovery have admitted that it may have a bit of an image problem. For example, in a recent review, several ...

Overcoming the resolution limit in a light microscope of around half a wavelength of light (about 250 nanometers) is one of ...

SIMIP enables high-resolution images rich in both chemical and spatial information. A quantum cascade laser (QCL) excites molecular vibrations while a spatial light modulator (SLM) generates striped ...

Deblurring by pixel reassignment remaps raw fluorescent microscopy images to sharpen images via pixel reassignment. Credit: Zhao and Mertz, doi 10.1117/1.AP.5.6.066004. Obtaining high-resolution ...

In a study published in Nature Methods on December 2, a research team led by Profs. Xu Tao and Ji Wei from the Institute of Biophysics of the Chinese Academy of Sciences has developed a ...

Researchers have shown that expensive aberration-corrected microscopes are no longer required to achieve record-breaking microscopic resolution. Researchers at the University of Illinois at ...

Advanced light microscopy techniques are giving scientists a new understanding of human biology and what goes wrong in diseases Katarina Zimmer, Knowable Magazine Innovative techniques are helping ...

It is the computational processing of images that reveals the finest details of a sample placed under all kinds of different light microscopes. Even though this processing has come a long way, there ...