Mutations in the tumor suppressor TP53 are a common cause of cancer, making the altered protein an attractive target for ...

A study demonstrates that the 'previous state' of blood stem cells plays a decisive role in the subtype of leukemia that develops. The new technique, called STRACK, allows monitoring of the evolution ...

Many people are familiar with histamine, a biological molecule that serves as a key driver of allergic reactions and other ...

Deafness, the most common sensorineural hearing loss at all stages of life, occurs either independently or as part of ...

A new study headed by teams at the Wellcome Sanger Institute, EMBL’s European Bioinformatics Institute (EMBL-EBI), and Open Targets has indicated how mutations that cause cancer drug resistance fall ...

A common mutation in the KRAS gene is associated with improved overall survival in pancreatic ductal adenocarcinoma (PDAC) compared with other variants, in part because the mutation appears to lead to ...

Researchers developed a single-cell sequencing method that simultaneously measures cancer-linked DNA mutations and gene activity in solid tissues. Applying the approach to human esophageal samples ...

Researchers have identified a method that can determine the effectiveness of breast cancer treatment earlier than is ...

Biological aging undeniably affects human cognitive function. 1 However, how this happens—the underlying factors, interactions, and processes—remains unclear. He and his team want to understand how ...