Until today, skin, brain, and all tissues of the human body were difficult to observe in detail with an optical microscope, since the contrast in the image was hindered by the high density of their ...

A new tissue expansion method enables scientists to use mass spectrometry imaging to simultaneously detect hundreds of molecules at the single cell level in their native locations. For biologists, ...

In a cramped, windowless room on the University of California, Berkeley, campus, two bespoke microscopes—each a Swiss Army ...

Chemists discover how key contrast agent works, paving a way to create new markers needed for correlative microscopy that can image the structure and signaling of cells at the same time. Two labs at ...

A newly developed microscopy technique allows, for the first time, the visualization of more than 30 protein markers simultaneously in the human brain and uses bioinformatics to analyze their spatial ...

TEMI mapping of lipid distribution across cerebellar layers. This image shows lipid species specifically enriched in three distinctive layers of the cerebellum: molecular layer, white matter layer and ...