Determining how somatic copy number alterations (SCNAs) promote cancer is an important goal. We characterized SCNA patterns in 4,934 cancers from The Cancer Genome Atlas Pan-Cancer data set.
CN signatures were prevalent across cancer types and associated with diverse processes including focal tandem duplications, seismic amplifications, genome-wide loss of heterozygosity (gLOH), and HRD.
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Christina Majaski writes and edits finance, credit cards, and travel content. She has 14+ years of experience with print and digital publications. Lea Uradu, J.D., is a Maryland state registered tax ...