A protein that quietly suppresses tooth growth may hold the key to regrowing teeth in adults, according to a line of research that has moved from mouse models to the doorstep of human clinical trials.

For decades, dentists and scientists have dreamed of helping people regrow lost teeth. Now, thanks to remarkable advances in genetics, molecular biology, and regenerative medicine, that dream is ...

Dr. Katsu Takahashi’s team developed TRG-035, an intravenous drug targeting the USAG-1 protein. This protein suppresses tooth development after adult teeth come in. By blocking USAG-1, the drug ...