Researchers identified key differences between two widely used multiple sclerosis models, showing how each can better study myelin damage, immune responses, and repair. The findings may improve ...

Epigenetic aging clocks use DNA methylation patterns to measure biological age and predict health risks across human tissues.

Microscopic images of human tissue are a cornerstone of biomedical research and clinical diagnostics. Yet despite their importance, these images often remain difficult to analyze systematically and to ...

For the first time, scientists have grown functional, brain-like tissue without using any animal-derived materials or added biological coatings. The development opens the door to more controlled and ...

Two models more accurately replicate the physiology of the liver, offering a new way to test treatments for fat buildup. More than 100 million people in the United States suffer from metabolic ...

A new paper in Biology Methods and Protocols, published by Oxford University Press, shows that scientists can train artificial intelligence models to distinguish brain tumors from healthy tissue. AI ...

University of Missouri researchers are developing new ways to better simulate the complex nature of human brain tissue. For years, scientists have worked to uncover how the brain responds to ...

As regulatory momentum accelerates globally to reduce reliance on animal testing, leading experts in microphysiological systems (MPS), complex in vitro models (CIVMs), organoids, and organ‑on‑chip ...

Infectious microbes have evolved sophisticated means to invade host cells, outwit the body’s defenses and cause disease. While researchers have tried to puzzle out the complicated interactions between ...

Animal models are established, important tools for preclinical safety and efficacy testing. Companies are advancing more “humanized” models to better reflect human responses, while at the same time ...