Clinical portfolio, informed by deep and novel synapse biology and pharmacology insights, aims to strengthen neural connections through event-driven pharmacology Lead candidate zelquistinel is ...

Spinogenix’s Fragile X Syndrome (FXS) drug is the first to show rescued well-established resting EEG abnormalities, ...

How do we think, feel, remember, or move? It all depends on transmission of chemical signals in the brain, carried and released by molecular containers called vesicles. In a new study, researchers ...

INDIANAPOLIS--(BUSINESS WIRE)--Gate Neurosciences, a clinical-stage biotechnology company using precision medicine to develop next-generation neuroscience therapies, today announced upcoming ...

Matrix metalloproteinases (MMPs) are a family of extracellular, zinc-dependent endopeptidases that have emerged as pivotal regulators of neural plasticity and synaptic function. In the brain, MMPs ...

Scientists disclose how mitochondria control tissue rejuvenation and synaptic plasticity in the adult mouse brain. Nerve cells (neurons) are amongst the most complex cell types in our body. They ...

Researchers have identified a narrow recovery period in the brain, roughly one hour after a stress event, during which a second natural pulse of the hormone corticosterone can restore disrupted ...

One fundamental feature of neurodegenerative diseases is a breakdown in communication. Even before brain cells die, the delicate machinery that keeps neurons in touch-by clearing away protein waste at ...

A DGIST research team identified that the mutation of the collybistin protein found in autistic patients weakens the brain's inhibitory synaptic function and leads to communication deficiencies. The ...

Research led by Shannon Farris, an assistant professor at the Fralin Biomedical Research Institute at VTC, found a mitochondrial mechanism that helps explain how CA2 neurons, like those highlighted ...

Glial cells, also known as neuroglia, are non-neuronal cells that play a crucial role in various neurophysiological processes. They not only support nervous system structures but also contribute to ...