A decade ago, the Nobel Prize in Chemistry was awarded to a trio of researchers for the development of super-resolved fluorescence microscopy. The announcement at the time stated that the researchers’ ...

To unravel the complexities of biological phenomena, scientists have long relied on microscopy to visualize the intricate details of their specimens, including tissue architecture, cell morphology, ...

Even those who maintain that super-resolution microscopy is a powerful tool of biological discovery have admitted that it may have a bit of an image problem. For example, in a recent review, several ...

eDL-cSIM: An AI-driven super-resolution imaging method that captures high-quality live-cell dynamics in a single exposure, enhancing speed, resolution, and environmental robustness for advanced ...

A research team drawn from collaborators across the USA has developed a super-resolution photoacoustic imaging method that ...

Super-resolution microscopy, or nanoscopy, enables the use of fluorescent-based molecular localization tools to study molecular structure at the nanoscale level in the intact cell. Analysis of ...

Fluorescence images of nuclei in a cell spheroid labeled by rsGamillus-S with a diameter of 100 µm observed with widefield, SPA-SIM, and 3DSIM at a depth of 43 µm. Credit: From Nature Methods (2024).

With the rapid revolution in super-resolution microscopy, the resolution of far-field optical microscopy has entered the sub-nanometer era, providing new insights into macromolecules in vitro and in ...

A new, nano-scale look at how the SARS-CoV-2 virus replicates in cells may offer greater precision in drug development, a Stanford University team reports in Nature Communications. Using advanced ...

The brain relies on real-time delivery of oxygen and nutrients through its microvasculature, which threads through neural tissue like electrical wires. While modern imaging technologies allow ...