Reveal Hidden Biology by Combining Long Fragment Target Capture with SMRT Sequencing While the power of whole human genome sequencing to fuel discovery is unparalleled, there are many research ...

Structural variations (SVs), including insertions, deletions, inversions, and substitutions, can profoundly influence gene ...

A new large-scale, high-throughput method — paired-end mapping (PEM) — for identifying structural variants in the human genome has been described. It provides insights into how these variants arise ...

Genome assemblies from 65 individuals, representing a variety of the world’s populations, are advancing the scientific exploration of complex genetic structural variation. Structural variations are ...

Structural variations (SVs)—large-scale changes in DNA sequence—play a crucial role in shaping traits such as yield, quality, and environmental adaptation in crops.

Questions: What are the ecological processes that determine the spatial distribution of species and species diversity? Partitioning beta diversity can provide fundamental insights into the processes ...

The most complex engineering of human cell lines ever has been achieved by scientists, revealing that our genomes are more resilient to significant structural changes than was previously thought.

Structural variants (SVs) reach up to the megabase scale and account for 10 times as many variants as single nucleotide polymorphisms in the human genome. They contribute to a range of normal and ...