Structural biology is used to understand the three-dimensional shape of biological molecules and how their shape enables them to function both inside and outside of cells. Furthermore, the ...

Dr. Hong Li, professor in Van Andel Institute’s Department of Structural Biology, leverages CRISPR, cryo-EM and other leading-edge technologies to explore the mechanisms underlying RNA-mediated ...

"The protein folding problem--the way in which unfolded proteins manage to reach their native, three-dimensional, functional form--has become a central focus for many scientists," declares Walter ...

Cryo-electron microscopy (cryo-EM) has revolutionalized our understanding of the intricate molecular machinery that governs life. It has elucidated the three-dimensional (3D) structure of biological ...

Barry Stoddard is a structural biologist. His research focuses on revealing the three-dimensional structures of proteins and modifying them to help treat or cure diseases like cancer, cystic fibrosis, ...

A research team reports that advances in protein design—especially when combined with artificial intelligence—are rapidly ...

Over the past decade, structural biology has been profoundly transformed by advances in computational power, algorithmic ...

Advancements to include CosMx® Whole Transcriptome Panel; enhanced technology engine to power CellScape™ for spatial proteomics; expansion to 1000-plex protein assay on GeoMx® DSP; and launch of ...

I. Rayment, H.M. Holden, M. Whittaker, C.B. Yohn, M. Lorenz. K.C. Holmes, R.A. Milligan, "Structure of the actin-myosin complex and its implications for muscle ...