Nature

Conversion of staphylococcal pathogenicity islands to CRISPR-carrying antibacterial agents that cure infections in mice

Figure 1: SaPI and ABD structures. As it has been reported that phage can cure a subcutaneous staphylococcus infection if administered IP 16, we performed a second test of ABD efficacy in the SC model ...
JSTOR Daily

Small RNA Genes Expressed from Staphylococcus aureus Genomic and Pathogenicity Islands with Specific Expression among Pathogenic Strains

Small RNA (sRNA) genes are expressed in all organisms, primarily as regulators of translation and message stability. We have developed comparative genomic approaches to identify sRNAs that are ...
Nature

The phage-related chromosomal islands of Gram-positive bacteria

Staphylococcus aureus pathogenicity islands (SaPIs) are highly mobile phage-related mobile genetic elements in staphylococci. Elements similar to SaPIs have been detected in related Gram-positive ...
Kaleido Scope

Microbial Pathogenesis Projects

Molecular piracy and the mobilization of Staphylococcus aureus pathogenicity islands Staphylococcus aureus is an opportunistic pathogen that can cause serious local and systemic infections in humans ...