This new review article highlights the pivotal and paradoxical role of R-loops in maintaining genomic stability while simultaneously posing risks to it. These three-stranded nucleic acid structures, ...
Image Caption: The factors contributing to R-loop formation. Several factors contribute to R-loop formation, including RNA components, specific DNA structures, histone and RNA modifications, ...
Kyle Miller and his team discovered a potential new target for drug therapies: structures in our DNA called R-loops. A human cancer cell that overexpresses the enzyme APOBEC3B (left) has fewer R-loops ...
A look at neurodegenerative disease in the context of the aging brain will test the link between peculiar genomic structures in the cells, called R-loops, known to cause DNA damage as we age and ...
New research reveals how the RapA enzyme protects against R-loop cytotoxicity in E. coli. Genetically speaking, it's a bacterium's worst-case scenario: during transcription, newly minted RNA sticks to ...
Some results have been hidden because they may be inaccessible to you
Show inaccessible results
Feedback