Ahmet Coskun's lab has developed iseqPLA to map protein interactions. An artistic rendering of sub-cellular activity: The cell membrane is seen at the top, nucleus on the bottom/right. Protein pairs ...

DNA-to-protein mapping could help researchers understand some health disparities. A new genetic mapping study led by researchers at the Johns Hopkins Bloomberg School of Public Health traces links ...

The dementia associated Tau protein — known for its role in microtubule regulation — has now been found to also play important roles in the nerve signaling and mitochondrial function in the brain. A ...

No protein is an island. Proteins interact to keep the machinery of the whole organism running. Without protein-protein interactions (PPIs), there would be no biochemical reactions, transmission of ...

A new genetic mapping study led by researchers at the Johns Hopkins Bloomberg School of Public Health traces links between DNA variations and thousands of blood proteins in two large and distinct ...

BUFFALO, N.Y. – A groundbreaking technique for in-depth mapping of protein localizations in whole tissue developed by researchers in the University at Buffalo School of Pharmacy and Pharmaceutical ...

Peptide mapping is an essential step in characterizing, identifying, and monitoring a wide range of properties of target proteins in biotherapeutic studies. Peptide mapping for biotherapeutic proteins ...

Drug development and production rely on stringent quality controls, reproducibility, and verification. Biopharmaceuticals, including protein-based therapies, require extensive characterization, ...

The spike protein of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been the primary target of many drug discovery efforts and is similarly utilized in each of the approved COVID-19 ...