Scientists at Université de Montréal and its affiliated Montreal Clinical Research Institute (IRCM) have uncovered unique roles for a protein complex in the structural organization and function of ...
The search space for protein engineering grows exponentially with complexity. A protein of just 100 amino acids has 20100 ...
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How a vital DNA protection protein complex adapts to new threats without compromising its essential functions
In Lewis Carroll's "Through the Looking-Glass," Alice is stuck in a never-ending race with the Red Queen yet never gains a lead. "It takes all the running you can do to keep in the same place," the ...
Protein function prediction and annotation represent critical challenges in the post‐genomic era. As high‐throughput sequencing continues to generate vast amounts of protein data, computational ...
In addition to exporting materials out of the nucleus, the protein, called Exportin-1 (also called Xpo1 or Crm1), seems to play a role in promoting gene transcription, the process that creates RNA ...
A team led by UT Southwestern Medical Center researchers has uncovered the atomic structure of a protein complex pivotal to the function of motile cilia, the hair-like structures extending from the ...
GBA1 mutations alone do not explain lysosomal dysfunction in PD. Loss of endosomal recycling proteins cripple this lysosomal enzyme. Without a protein called COMMD3, cells spit out would-be lysosomal ...
To ensure that protein production in our cells runs smoothly, the protein complex NAC slows down the rate of protein synthesis right at the start. An international research team with significant ...
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MULTI-evolve accelerates protein engineering with machine learning
The search space for protein engineering grows exponentially with complexity. A protein of just 100 amino acids has 20^100 possible variants-more combinations than atoms in the observable universe.
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