The search space for protein engineering grows exponentially with complexity. A protein of just 100 amino acids has 20100 possible variants—more combinations than atoms in the observable universe.

A team led by Prof. WANG Chao and Prof. HUANG Chengdong from the University of Science and Technology of China (USTC) of the Chinese Academy of Sciences (CAS) revealed the molecular mechanism of ...

Respiratory supercomplex formation relieves molecular strain of mitochondrial membranes and reshapes global protein motions, linking membrane reorganization to respiratory function.

Proteins, the pillars of cellular function, often assemble into 'complexes' to fulfill their functions. A study reveals why this assembly often begins during the very process of protein synthesis or ...

The search space for protein engineering grows exponentially with complexity. A protein of just 100 amino acids has 20^100 possible variants-more combinations than atoms in the observable universe.

A recent article in Small describes a modular platform for assembling protein-DNA composites using covalent, site-specific conjugation. This method enables the formation of stable structures with ...

These proteins depend on their partner because they are rapidly degraded if they are not combined into complexes as soon as they are made. Proteins, the pillars of cellular function, often assemble ...