To understand the human genome, scientists focused on protein-coding genes and their functions for decades. This has given us ...
Biologists have discovered a new type of RNA-splicing regulation that helps to determine which protein-coding exons will be included in messenger RNA transcripts. RNA splicing is a cellular process ...
Thousands of new genes are hidden inside the “dark matter” of our genome. Previously thought to be noise left over from evolution, a new study found that some of these tiny DNA snippets can make ...
Proteoforms, the diverse molecular variants of proteins, are key to understanding cellular functions, disease mechanisms, and biomarker discovery in proteomics.
Like islands scattered across a vast intergenic sea, the nearly 20,000 protein-coding genes within the human genome represent a mere 2 percent of its 3 billion base pairs. When, where, and to what ...
Researchers have successfully repaired damaged mouse hearts using a protein from zebrafish. They discovered that the protein Hmga1 plays a key role in heart regeneration in zebrafish. In mice, this ...
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