A team of researchers at the University of Cologne’s Center for Biochemistry, together with the Bambino Gesù Pediatric Hospital in Rome, Italy, have discovered a fundamental biological mechanism that ...

Selective ASO-based JAK2 inhibitor for the treatment of hematological malignancies with JAK2 V617F mutation burden. Use of causal modeling to uncover cell-cell communication dynamics in the tumor ...

In the fight against disease, programmed cell death – also known as apoptosis – is a key protective function of the body. It breaks down cells that are damaged or have undergone dangerous changes.

New basic science insights into programmed cell death could offer relief for inflammatory bowel disease. Many people with IBD, an umbrella term that includes ulcerative colitis and Crohn's disease, ...

Researchers have discovered how to block cells dying, in a finding that could lead to new treatments for neurodegenerative conditions like Parkinson's and Alzheimer's. The team at WEHI, including ...

Cells in our body are programmed to die after a certain period of time—a natural process known as apoptosis or “cell suicide.” This process is essential for maintaining the body’s balance. When aged ...

A surprising new function of essential hearing proteins may explain why some genetic mutations and common antibiotics lead to permanent deafness.

RIPK1 inhibition reduced inflammation and keratinocyte cell death in lichen planus and CLE models. Could this be a new treatment approach? Read more.