In preliminary experiments with mice and lab-grown cells, Johns Hopkins Kimmel Cancer Center scientists have found that a protein-signaling process accelerates the work of the gene most frequently ...

The immune system provides an integral defense against cancer growth and progression. Activating an anti-tumor immune response relies on several biological steps that can ultimately result in the ...

A tissue section from a mouse model of lung metastasis showing cancer cells (green) that have attracted and activated fibroblasts (red) to support the growth of a metastatic tumor. Image: Massagué Lab ...

Scientists have discovered that T cell receptors activate through a hidden spring-like motion that had never been seen before ...

Cell signaling is crucial for cells to communicate and function correctly. Disruptions in these pathways, caused by genetic mutations or environmental factors, can lead to uncontrolled cell growth, ...

Jagged-2, a signaling protein, may be a potential therapeutic target for slowing or halting the progression of PAH, according ...

The journey started with an enigma in the zebrafish embryo: some endothelial cells, actively involved in the initial stages ...

In a groundbreaking study on the synthesis of cellulose—a major constituent of all plant cell walls—a team of Rutgers University-New Brunswick researchers have captured images of the microscopic ...

The field of sepsis research has advanced significantly in recent years, particularly regarding the interplay between immune responses and multiple forms of ...

The process of aging is associated with a decline in immune functions and persistent low-level inflammation. Now, researchers ...