A new study looked at 926 polygenic risk scores for 310 diseases. It found that, on average, only 11% of individuals who develop disease are identified, while at the same time 5% of people who do not ...

Polygenic scores are a source of considerable debate in the biomedical and healthcare communities. Can they or can they not provide information that can be used in the prevention of common complex ...

Incorporating a polygenic risk score into prostate cancer screening could enhance the detection of clinically significant prostate cancer that conventional screening may miss, according to results of ...

Using polygenic risk scores along with positive family histories and breast cancer-associated gene mutations improves risk stratification for breast cancer screening. Compared with a lower polygenic ...

The optimism is not unfounded. In specific, well-defined clinical scenarios, polygenic scores are beginning to demonstrate some tangible utility. For cardiovascular disease, MI-GENES, a 10-year follow ...

An international expert group has published the first evidence-based clinical guidance on the use of polygenic risk scores (PRSs) for breast cancer. Published in the peer-reviewed journal Cancers, the ...

Millions struggle with depression and anxiety, often enduring long waits for effective treatment. Scientists in Sweden, Denmark, and Germany are developing a genetic test to predict which medications ...

Please provide your email address to receive an email when new articles are posted on . Researchers developed a multi-ancestry polygenic score using data from two genome-wide association studies.