USA: Researchers have discovered in a new research that bronchodilator responsiveness (BDR) shows a stronger association with ...

Polygenic risk scores (PRS) combined with clinical factors improve POAG risk prediction, aiding in identifying high-risk patients. The study used OHTS data, showing low polygenic risk correlates with ...

The results of research by scientists at University College London (UCL), Imperial College London, and the MRC Laboratory of Medical Sciences, indicate that a potentially life-changing heart condition ...

Polygenic background bidirectionally modifies the penetrance of pathogenic variants in hypertrophic (HCM) and dilated (DCM) ...

A polygenic risk score (PRS) may help identify women who are at a greater risk of developing a future breast cancer after treatment for in situ breast disease, a retrospective study suggests. The ...

Incorporating a polygenic risk score into prostate cancer screening could enhance the detection of clinically significant prostate cancer that conventional screening may miss, according to results of ...

Patients who learn their likelihood of developing CAD not only from the Framingham Risk Score but also from a more-personalized polygenic risk score experience fewer major adverse cardiovascular ...

A polygenic risk score was able to detect a high proportion of clinically significant prostate cancer. Cancer would not have been detected in 71.8% of patients with the use of PSA or MRI screening.

“What makes the score so powerful is its ability to predict, before the age of five, whether a child is likely to develop obesity in adulthood, well before other risk factors start to shape their ...