Dr. Kaneez Fatima Shad knows that the “Patch Clamp” method needs skills and patience. It takes the whole day to craft only one sample and even a small leak could alter the results drastically.

Scientists applied molecular dynamics simulations to visualize how potassium ions pass through a potassium ion channel at atomic resolution for the first time. (Nanowerk News) The patch clamp ...

Despite the importance of the mammalian neocortex for complex cognitive processes, we still lack a comprehensive description of its cellular components. To improve the classification of neuronal cell ...

To record ion channel activity across cell membranes the conventional patch clamp remains the gold standard and is widely used in drug discovery research. However, this traditional method requires ...

High-throughput screening (HTS) is a drug discovery strategy used extensively during early-stage pharmaceutical development. The patch-clamp technique remains the gold standard for testing the ...

Flip-the-Tip Technology Uses Standard Glass Pipettes to Achieve Higher Throughput in Ion Channel Screening The pharmaceutical industry has widely recognized patch clamping as the “gold standard” to ...