The Notch pathway is a conserved ligand–receptor signaling mechanism that modulates cell fate and differentiation (Greenwald, 1998; Artavanis-Tsakonas et al., 1999). The Notch receptor is a ...

A cellular signal essential to the development of the skeleton increases during aging to weaken bones, finds a new study in mice. The study, led by researchers from NYU Grossman School of Medicine, ...

Metazoans use a handful of highly conserved signaling pathways to create a signaling backbone that governs development. How these few signals have such a versatile action likely depends upon the ...

A cellular signal essential to development of the skeleton increases abnormally during aging to weaken bones. A cellular signal essential to the development of the skeleton increases during aging to ...

Mitochondrial morphology in myotubes and muscle stem cells coordinate to control Notch signaling via MAM. You are free to share and adapt the material. Attribution is required.