Natural selection shapes genomes to evolve and to adapt but, are the rules of natural selection also applying to cancer genome evolution? An interdisciplinary team of scientists at the Centre for ...
The fixation probability is given for heterozygous, harmful mutations. The vertical line indicates selection coefficients that satisfy Nes = 0.5 and roughly separates the domains where genetic drift ...
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infects cells by binding to angiotensin-converting enzyme 2 (ACE2) sites on epithelial cells. This is mediated by the spike protein, which ...
Beijing Zhongke Journal Publising Co. Ltd. In summary, this work provides aninnovative strategy to ease CRISPR mutant identification and Cas9 transgene elimination using a single selection marker, ...
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