Mutations in the tumor suppressor TP53 are a common cause of cancer, making the altered protein an attractive target for ...

Deafness, the most common sensorineural hearing loss at all stages of life, occurs either independently or as part of ...

A research team at the University of Konstanz, led by toxicologist Ivano Amelio, has demonstrated how differently individual mutations of the tumor suppressor p53 affect pancreatic carcinomas. When ...

A groundbreaking study published in this week’s issue of PNAS by scientists from Israel and Ghana shows that an evolutionarily significant mutation in the human APOL1 gene arises not randomly but more ...

In a recent study published in the journal Nature Biotechnology, researchers in Switzerland used base and prime editing to create and analyze a wide array of variants of the epithelial growth factor ...

OnKure Therapeutics, Inc. (OKUR) is gearing up for a major event in Q4 of 2024, which is that it intends to release data from its phase 1 PIKture-01 study using OKI-219 for the treatment of solid ...