An HIV-derived nucleoside therapy now treats rare genetic diseases by restoring mitochondrial DNA and improving muscle ...

In a finding that opens the door to the development of targeted therapies for various muscle disorders, newly published research identifies key mechanisms of skeletal muscle regeneration and growth of ...

Researchers have discovered a mechanism in our cells that is essential to energy production in the muscles. The discovery may lead to new treatment for disorders affecting the muscles, like diabetes, ...

Scientists at the University of Cincinnati and colleagues report that a regulatory protein found in skeletal muscle fiber may play an important role in the body’s fight or flight response when ...

Muscle weakness may be due to a chronic condition or an infection. Conditions that can weaken muscles include Addison’s disease, anemia, diabetes, fibromyalgia, and more. Muscle weakness is a lack of ...

Panel A shows the microscopic myoarchitecture of the circular and longitudinal muscle layers of the lower esophageal sphincter and stomach. The circular muscle fibers of the esophagus cross each other ...

For most people, swallowing is second nature, but how does it occur, and why do some people have difficulty with it? Researchers at Kyushu University in Japan have started to tackle these questions by ...

The type 1 ryanodine receptor (RyR1) is an important calcium release channel in skeletal muscles essential for muscle contraction. It mediates calcium release from the sarcoplasmic reticulum, a ...

Researchers engineered mice with a mutation (E3896A) in the RyR1 calcium-binding site, eliminating calcium-induced calcium release (CICR) without affecting depolarization-induced calcium release. The ...

Muscle dysmorphia (MD) is a psychopathological condition — which means that it affects your thoughts and behaviors in problematic ways. People with muscle dysmorphia are obsessively concerned with ...

Patients with degenerative diseases that attack skeletal muscle tissues, such as Duchenne muscular dystrophy, may soon benefit from novel stem cell therapies. A study has demonstrated how new skeletal ...