Scientists discovered that lowering a specific molecule helps microglia switch into a protective state that quiets brain inflammation in Alzheimer’s. A small group of these cells seems to have an ...

Tiny immune cells called microglia protect the central nervous system (CNS) in a multitude of ways: They provide innate immunity, shape neurodevelopment, maintain homeostasis and modulate neurological ...

Microglia, the primary immune cells in the brain, play vital roles in neurogenesis, homeostasis maintenance, synaptic plasticity, and brain development. They are widely used in monoculture for ...

In this interview, Dr. Tilman explains the functions of iPSC-derived microglia and their relevance to conditions like Alzheimer’s and other neurodegenerative diseases. Microglia are the primary immune ...

This image shows how human iPSCs in which the microglia-specifying six-TF cocktail is switched on (lower row), in contrast to iPSCs in which they remain switched off (upper row), abandon their ...

Microglia are essential for healthy brain function. Defective microglia are increasingly linked to the development of neurodegenerative disorders. “Microglia are unique,” says Prof. Movahedi. “They ...