Figure 1: Generation and characterization of MHC II-EGFP knock-in mice. Maturation of MHC class II molecules, monitored by pulse-chase analysis and digestion with endoglycosidase H, occurs normally in ...
Whether most MHC class II-bound ligands on the cell surface of antigen-presenting cells (APCs) arise from the binding of short peptides after degradative processing (cut first, bind later), or whether ...
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