At the onset of diabetic cardiomyopathy, Trdn-as expression increases, which regulates the methylation of Casq2 mRNA mediated by METTL14, thus increasing the stability and expression of Casq2 mRNA.
A study in mouse models and human tissue, carried out by researchers at the Barcelona Institute of Science and Technology Centre for Genomic Regulation (CRG), has found that the small nuceleolar RNA ...