Colorectal cancer (CRC) remains one of the most prevalent and deadly cancers worldwide, with rising incidence linked to dietary and lifestyle changes. Despite advances in surgery and chemotherapy, ...

A new review article highlights the powerful influence of long non-coding RNAs (lncRNAs) in regulating natural killer (NK) cells, revealing promising opportunities to enhance immune responses and ...

In the post-genomic era, long non-coding RNAs (lncRNAs) have emerged as critical regulators in various cancers and hold potential as minimally invasive diagnostic biomarkers. This study aimed to ...

Scientists at the University of Pittsburgh, together with colleagues at the University of Pittsburgh School of Medicine and University of Pittsburgh Cancer Institute, have identified how a long ...

Impact of variant allele frequency (VAF) of TP53 alterations and Signatera circulating tumor DNA (ctDNA) monitoring for patients (pts) with advanced urothelial carcinoma (aUC) treated with enfortumab ...

Digital spatial profiling of advanced solid tumors and lymphomas from a phase 1 trial of copanlisib and nivolumab. Using single-cell sequencing to identify endothelial expression of immune checkpoint ...

The polarization of macrophages is crucial in modulating the tumor microenvironment and impacting cancer development. Long noncoding RNAs (lncRNAs) have been identified as key regulators in this ...

Long non-coding RNAs (lncRNA) are a type of RNA molecule that do not carry instructions to make proteins. Instead, they influence how other genes are expressed. There are tens of thousands of lncRNAs ...