Researchers have developed a new compound, ZTA-261, that binds to thyroid hormone receptor beta (THR ). THR plays an important role in the regulation of lipid metabolism, which affects lipid levels in ...

Pro-inflammatory cytokines (TNF-α, IL-6, and IL-1β) are produced in large quantities locally in the joints and subsequently enter the bloodstream. TNF-α and IL-6 may promote LDL metabolism by ...

In a 15-patient, Phase 1, first-in-human trial, a one-time CRISPR-Cas9 gene-editing therapy safely reduced LDL cholesterol and triglycerides in people with difficult-to-treat lipid disorders, ...

In addition to providing energy, lipids are also essential building blocks of our cell membranes. However, despite their ...

Chanarin-Dorfman syndrome (CDS) is a rare autosomal recessive disorder manifesting predominantly as congenital ichthyosiform erythroderma and systemic accumulation of neutral lipids. Mutations in the ...

A team of medics performing CPR and inserting an IV drip on a patient lying unconscious in a hospital bed. [iStockphoto] When 19-year-old *Jeffrey walked into Aga Khan Hospital after suffering a heart ...

Clinicians receive conflicting advice on whether to order blood tests to screen for lipids in children. A new study could add to the confusion. Researchers found that a combination of physical proxy ...

Published on A landmark atlas shows lipids rely on specialised transporters to reach their cellular targets. In addition to providing energy ...

VK2809 is an orally available, tissue and receptor-subtype selective agonist of the thyroid hormone beta receptor (TRβ) that possesses selectivity for liver tissue, as well as the beta receptor ...

In addition to providing energy, lipids are also essential building blocks of our cell membranes. However, despite their ...