When measuring with light, the lateral extent of the structures that can be resolved by an optical imaging system is fundamentally diffraction limited. Overcoming this limitation is a topic of great ...

Imagine you’re sitting at a pond, listening to the din of croaking frogs. You want to know how many frogs are in the pond, but you can’t pick out the individual croaks—only the combined sound rising ...

Super-resolution (SR) fluorescence microscopy, through the use of fluorescent probes and specific excitation and emission procedures, surpasses the diffraction limit of resolution (200~300 nm) that ...

Microscopes have long been scientists’ eyes into the unseen, revealing everything from bustling cells to viruses and nanoscale structures. However, even the most powerful optical microscopes have been ...

Schematic of the threshold tracking and lock-in technology. Deterministic creation of single-photon colour centres. High reproducibility, high brightness, and high durability of single-photon single ...

A new two-photon fluorescence microscope developed at UC Davis can capture high-speed images of neural activity at cellular resolution thanks to a new adaptive sampling scheme and line illumination.