Light microscopy is a cornerstone in life sciences technology, having experienced considerable diversification since its inception. This development becomes visible when considering the distinctive ...

Light-sheet microscopy has emerged as a transformative imaging modality that enables rapid, three‐dimensional visualisation of biological specimens with minimal photodamage. By illuminating samples ...

Light-sheet microscopy is an extremely versatile imaging technique with a vast range of implementations that are typically designed with the needs of the sample in mind. By illuminating samples with a ...

ZEISS and Alpenglow Biosciences today announced a new partnership to jointly develop an inverted light-sheet microscope and bioinformatics pipeline tailored specifically for clinical applications.

descSPIM enables three-dimensional imaging of diverse tissues like neural cells and cancerous tumors. The widespread dissemination and adoption of descSPIM can accelerate biomedical discoveries. Three ...

Researchers have incorporated a swept illumination source into an open-top light-sheet microscope to enable improved optical sectioning over a larger area of view. The advance makes the technique more ...

Analyzing the response of cells to heat shock is an established way to study the behavior of cells in changing conditions, and understand their natural survival mechanisms. A project at the University ...

Light-sheet microscopy (LSM) techniques are designed to illuminate thin slices of a larger sample with perpendicular laser illumination, as a way to improve signal-to-noise performance and reduce ...

During image analysis, researchers use light sheet microscopy of cleared tissue as a preferred method for high throughput volumetric imaging. A flexible system can provide a range of sizes, resolution ...

Researchers developed a large-scale, dynamic imaging technique using mesoscopic oblique plane microscopy, which can capture 3D images of entire organisms and maintain cellular resolution. A new ...

Light-sheet microscopy is a rapidly developing field thanks to the numerous benefits and vast number of implementations when imaging with a light sheet. However, these benefits are best realized when ...