Did you know the appendix is not completely useless? Doctor explains the function of ‘vestigial’ organ

While it is possible to survive without the appendix, the organ helps maintain gut health by protecting the gut microbiome, ...
Nature

Differential toxicity to murine small and large intestinal epithelium induced by oncology drugs

Gastrointestinal toxicity is a major concern in the development of drugs. Here, we establish the ability to use murine small and large intestine-derived monolayers to screen drugs for toxicity. As a ...
Business Wire

Emulate Publishes Results for Intestine-Chip Populated with Organoids; Data Demonstrates Superior Human-relevant Intestine Function than Organoids Alone

Emulate’s Duodenum Intestine-Chip provides a robust system for preclinical drug assessment of drug transport, metabolism, and drug-drug interactions in the intestine BOSTON--(BUSINESS WIRE)--Emulate, ...
Nature

Angulin-2/ILDR1, a tricellular tight junction protein, does not affect water transport in the mouse large intestine

Water is essential for all living things. In the intestinal tract, more than 10 L of water is (re)absorbed per day in humans. It is estimated that the colon absorbs about 90% of the water that enters ...