Researchers showed that a severe drop in NAD+—a core energy molecule—drives Alzheimer’s pathology in both human brains and mouse models.

A groundbreaking study reveals that researchers successfully reversed Alzheimer's disease in mice, restoring memory and ...

For over a century, Alzheimer's disease (AD) has been considered irreversible. Consequently, research has focused on disease prevention or slowing, rather than recovery.

Alzheimer’s researchers have long wished for better mouse models. That is now coming true. Scientists at the Jackson Laboratory in Bar Harbor, Maine, are cranking out numerous lines that express ...

One of those genes encodes the enzyme DHDDS, part of the pathway that glycosylates proteins in higher cells. Retinitis pigmentosa from DHDDS mutations is called RP59. This is a recessive genetic ...

A team of biostatisticians led by University of Pittsburgh School of Public Health scientists report “Transcriptomic congruence analysis for evaluating model organisms” in PNAS that they’ve developed ...

A team of scientists in France recently developed a mouse-adapted strain of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that efficiently replicates in the lungs of standard laboratory ...

The great majority of how we understand human disease, and attempt to cure it, derives from mice genetically fashioned to be prolific breeders, docile and easy to handle – all qualities that have made ...

Alzheimer’s has long been considered irreversible, but new research challenges that assumption. Scientists discovered that severe drops in the brain’s energy supply help drive the disease—and ...