A risky but often lifesaving surgery that removes damaged parts of the small intestine can leave patients facing a new threat: serious liver damage with no available treatment. Now, scientists have ...

Theoretically, for drugs that easily penetrate the intestinal mucosa, reduced villus blood flow could delay diffusion and, therefore, the rate of absorption. For example, the absorption rate for ...

New research shows that certain flavonols from everyday foods can shut down the body’s drug-resistance machinery, potentially paving the way for more effective treatments, but clinical hurdles remain.

Although the liver is not a major site of de novo cholesterol synthesis, it plays a central role in regulating plasma LDL-C levels. [12] This occurs because the liver is the principal site for both ...

Before orally administered drugs can make their way throughout the body, they must first bind to membrane proteins called drug transporters, which carry compounds across the intestinal tract and help ...