Patients with a severe traumatic brain injury (and not in shock because of blood loss) who received out-of-hospital administration of hypertonic fluids (a solution with increased concentration of ...

October 7, 2010 — The largest clinical trial to date of out-of-hospital hypertonic resuscitation shows it does not improve outcomes after traumatic brain injury. The disappointing results call into ...

April 6, 2009 — Hypertonic saline administered acutely to patients in hemorrhagic shock provides no survival benefit, according to interim results of a large, multicenter trial stopped early by the ...

Intravenous administration of isotonic fluids is the standard emergency treatment in the US for patients with severe blood loss, but bioengineering researchers have reported improved resuscitation ...