Despite being an essential developmental process, the understanding of human embryonic genome activation is limited, owing to the lack of in vitro cell models and ethical concerns. To advance ...

The onset of embryo-specific gene transcription, also known as embryonic genome activation (EGA), is a crucial step in the developmental journey of an organism. Although EGA has been studied to some ...

Researchers have used naïve pluripotent stem cells to create an embryo model that looks and acts like a natural human embryo. They say it’s an ethical way of gaining a better understanding of ...

At some point in our evolution, we lost the ability to activate a reproductive mechanism called embryonic diapause, which slows development, usually during the blastocyst stage. And so, unlike mammals ...

Descriptions of the embryo go back at least to the time of Aristotle, but it has only been since the late 19 th century and early 20 th century that advances in experimental approaches allowed ...

A recent study in Advanced Science presents a method for studying early human embryology by bioprinting epiblast-like structures from human-induced pluripotent stem cells (hiPSCs). The model forms a ...

In some mammals, the timing of the normally continuous embryonic development can be altered to improve the chances of survival for both the embryo and the mother. This mechanism to temporarily slow ...

The team observed the emergence of the three-dimensional embryo-like structures under a microscope in the lab. These started producing blood (seen here in red) after around two weeks of development - ...

Researchers at Newcastle University in England report they have coaxed the first human sperm cells from embryonic stem cells, in a remarkable demonstration of how quickly the field of stem-cell ...

Only about one out of three conceptions leads to birth. 1 Approximately a third of embryos fail to attach to the uterus, while another third is lost after the embryo implants. “Human reproduction is ...