The patient in Louisiana who was hospitalized with severe bird flu illness was found to have a mutated version of the virus, the U.S. Centers for Disease Control and Prevention (CDC) announced last ...

Unique mutations in the H5N1 strain enhance replication in human cells and cause severe disease in mice. The virus has spread from birds to mammals, including dairy cows, and infected humans, with one ...

Humanized mouse models are essential for investigating human gene function; however, the complete replacement of mouse genes ...

Traditional biochemical methods of studying human gene mutations are often laborious and costly. Now bioengineers at the University of California San Diego have developed a new simple approach to ...

(Reuters) - The U.S. Centers for Disease Control and Prevention said on Thursday its analysis of samples from the first severe case of bird flu in the country last week showed mutations not seen in ...

Tiny genetic alterations could help the bird flu virus enter cells in the upper respiratory tract, the C.D.C. said. But there is no sign that mutations are widespread in nature. By Benjamin Mueller ...

Helen Branswell covers issues broadly related to infectious diseases, including outbreaks, preparedness, research, and vaccine development. Follow her on Mastodon and Bluesky. You can reach Helen on ...

In 1992, Judith Frydman, PhD, discovered a molecular complex with an essential purpose in all of our cells: folding proteins correctly. The complex, a type of "protein chaperone" known as TRiC, helps ...

Understanding human gene function in living organisms has long been hampered by fundamental differences between species.