A study in the Chinese Journal of Natural Medicines reports the first high-resolution structure of the major G-quadruplex in the TMPRSS2 promoter and shows how berberine binds and stabilizes it, ...

DNA is the blueprint of life. Genes encode proteins and serve as the body's basic components. However, building a functioning organism also requires precise instructions about when, where, and how ...

Studying how single DNA molecules behave helps us to better understand genetic disorders and design better drugs. Until now however, examining DNA molecules one-by-one was a slow process.

Researchers at Aarhus University have built a DNA nanostructure shaped like a bacteriophage needle that can recognize ...

Similarly to the artistic technique of folding paper into ornate shapes, DNA origami is a self-assembling technique of precisely folding single-stranded DNA scaffolds into well-defined nanostructures.

Nucleic acids such as DNA and RNA play a central role in gene therapies and vaccines. They store and transmit biological ...

Scientists from the University of Sheffield, the MRC Laboratory of Medical Sciences (LMS) and Imperial College London have helped solve a decade-long ...