DNA doesn’t just sit still inside our cells — it folds, loops, and rearranges in ways that shape how genes behave. Researchers have now mapped this hidden architecture in unprecedented detail, showing ...

Deoxyribonucleic acid (DNA) replication is fundamental to life, yet the precise mechanics of how helicases unwind the genome for replication remain unclear. A recent study published in Nature used ...

MSK researchers are shedding new light on G-quadruplexes, a type of secondary DNA structure that can cause DNA replication to stall. The structures are a potential therapeutic target in cancer. Image ...

An HIV-derived nucleoside therapy now treats rare genetic diseases by restoring mitochondrial DNA and improving muscle ...

A Northwestern Medicine study has revealed a previously unknown connection between two fundamental cellular processes, ...

Harvard Medical School researchers have uncovered crucial insights into how an emerging class of antiviral drugs works.

Researchers at The Institute of Cancer Research, London identified the CIP2A–TOPBP1 complex as a master regulator of DNA repair during mitosis, coordinating backup pathways that protect chromosomes ...

Researchers have discovered how cells activate a last-resort DNA repair system when severe damage strikes. When genetic ...

Members of a new class of antivirals are being tested in U.S. clinical trials, and one has gained approval in Japan, but how ...

For decades, biology textbooks taught that DNA’s story could be told with a single image: two elegant strands twisting in a ...

The origin of life on Earth becomes even more fascinating and complex as we peer into the mysterious world of viruses.