New research shows how certain orphan noncoding RNA — oncRNA — can be predictable enough to be a ‘bar code’ identifying ...

Researchers have built a series of CRISPR-based platforms that can switch endogenous genes on and, just as critically, dial the activation level up or down by adjusting a small-molecule dose. The work ...

Even without deep computational skills, scientists can use the CRISPRware program to quickly browse entire libraries of precomputed guide RNAs for six model organisms, zoom in on their gene or region ...

The research team demonstrated that the targeted RNA acetylation system, guided by guide RNA that locates specific RNA within cells, can introduce acetylation chemical modifications to desired RNA.

Peking University, June 27, 2025: To overcome the inherent challenge of translation termination interference caused by stop codon reprogramming in mammalian cells, researchers from Peking University ...

DNA is transcribed into RNA, which is then translated into proteins. This is the central dogma of molecular biology – a mantra taught to every biology undergraduate student to be recalled and expanded ...

RNA epigenetics also called Epitranscriptomics is an evolving field of research that explores chemical modifications on RNA and their impact on the cell and ...

CRISPR functions as a programmable genetic memory system derived from bacterial immune defenses against viral infections. Guide RNA allows for rapid multiplexed targeting compared to older ...

< Photo 1. (From left) Professor Won Do Heo and Jihwan Yu, a Ph.D. Candidate of the Department of Biological Sciences > CRISPR-Cas13, a powerful RNA-targeting technology is gaining increasing ...

On June 11, 2025, the United States Court of Appeals for the Federal Circuit affirmed the Patent Trial and Appeal Board (PTAB) decision invalidating two patents owned by Agilent Technologies. The ...